TAP 700 are highly spherical starter pellets in size ranges from 600 µm to 800 µm. They consist of 100 % tartaric acid. They act as a pH modifier and as carrier systems in extended release formulations of weakly basic drugs. These drugs typically show bad solubility in higher pH environment such as in the lower intestinal tract which can be enhanced by the use of TAP as a starter core.

See pellet technologies for a detailed description.

Weakly basic actives DoE parameter spaceGlatt

Water-insoluble weakly basic actives on tartaric acid beads – a DoE case study

Abstract Yes, the headline is long, the overall topic not easy,…
Dabigatran Formulation for Oral Administrationingredientpharm

Dabigatran Formulation for Oral Administration – an Evaluation

Abstract Dabigatran etexilate mesylate is a pro-drug of Dabigatran…
Pellet sizes for potential BSC Class IV MUPS and capsule formulations.ingredientpharm

BSC Class IV APIs in oral formulations

APIs of BSC Class IV in oral formulations represent one of four…

Influence of tartaric acid pellets on the release behavior of a basic drug

Abstract The objective of this study is to investigate the influence…

Tartaric acid starter pellets as pH-modifier for basic drugs

Introduction We will introduce tartaric acid starter pellets…