TAP is a great offering for our clients that have a drug that shows pH dependent solubility and requires an acidic environment to improve solubility, release, and absorption. The TAP pellets can do a great job of creating the acidic microenvironment required to make their drug successful.
APIs with poor solubility in alkalic media, like in the intestine, sometimes need a kick with a small acidic environment and we are happy to support our customers with TAP® as excipient for this dilemma.
Our project partners love to work with TAPs, as they accelerate the dissolution rate of weakly basic drugs creating the best in-situ micro-environment conditions. You get TAPs in diverse sizes – perfect for multi-particulate formulations!