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TAPs. The safe and easy way to multi-particulate dosage forms

Multi-particulate dosage forms have striking advantages compared to monolithic dosage forms, such as:

  • low variability of gastric emptying
  • low dependency on nutrition state
  • low risk of localized high drug concentrations in the GI
  • reduced risk of sudden dose dumping
  • lower intra- and inter-individual variability
  • high control on time and place of drug delivery

This means firstly higher safety and secondly better compliance for your patients, and added-value for your products.

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    Satisfied partners

    TAP is a great offering for our clients that have a drug that shows pH dependent solubility and requires an acidic environment to improve solubility, release, and absorption. The TAP pellets can do a great job of creating the acidic microenvironment required to make their drug successful.

    APIs with poor solubility in alkalic media, like in the intestine, sometimes need a kick with a small acidic environment and we are happy to support our customers with TAP® as excipient for this dilemma.

    Our project partners love to work with TAPs, as they accelerate the dissolution rate of weakly basic drugs creating the best in-situ micro-environment conditions. You get TAPs in diverse sizes – perfect for multi-particulate formulations!

    Formulation Support

    contact your reliable partner

    The development of solid dosage forms with tartaric acid pellets is one of Glatt Pharmaceutical Services’ specialty, with focus on complex formulations and vast expertise for multiparticulate systems. The development and manufacturing centers with FDA and EU-GMP certification are well equipped for all your requirements. New technologies are in charge for the realization of your product ideas. Also for demanding ingredients.

    • Sites and cGMP facilities in Germany & USA
    • Strong core competence
    • Solution oriented
    • Flexible setup
    • Full service
    Pharmaceutical_Services

    Product information: Tartaric Acid Pellets

    Product, standard sizesSize
    TAP 200100-355 µmmore details
    TAP 300200-355 µmmore details
    TAP 400300-500 µmmore details
    TAP 500400-600 µmmore details
    TAP 600500-700 µmmore details
    TAP 700600-800 µmmore details
    Product, narrow sizes
    TAP 300-425300-425 µmmore details
    TAP 425-500425-500 µmmore details
    TAP 425-600425-600 µmmore details
    TAP 425-600 PSD500-600 µmmore details
    TAP 500-600500-600 µmmore details
    TAP 700 PSD600-710 µmmore details
    TAP 850-1000850-1000 µmmore details

    TAPs are best solution for weakly basic API. No fitting pellet sizes found? Not the right material?

    Case Studies & Application notes

    API_TAP_formulation

    Influence of tartaric acid pellets on the release behavior of a basic drug

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    Abstract The objective of this study is to investigate the influence…