TAP are highly spherical starter pellets consisting of 100 % tartaric acid. They act as a pH modifier and as carrier systems in extended release formulations of weakly basic drugs. These drugs typically show bad solubility in higher pH environment such as in the lower intestinal tract which can be enhanced by the use of TAP as a starter core.
Introduction: Weakly Basic Drugs and the Role of Acidic Microenvironments
Weakly…
https://tapellets.com/wp-content/uploads/2026/01/weakly-basic-drugs-that-benefit-from-acidic-environments-small.jpg385661Bastian Arlthttps://tapellets.com/wp-content/uploads/2021/03/ingredientpharm-700x240-1-300x103.pngBastian Arlt2026-02-12 12:23:192026-02-12 12:23:19Weakly Basic Drugs That Benefit from Acidic Environments in Modern Pharmaceutical Formulation
Introduction to Weakly Basic Actives in Oral Formulation
Yes,…
https://tapellets.com/wp-content/uploads/2022/07/parameter-space.jpg772823Bastian Arlthttps://tapellets.com/wp-content/uploads/2021/03/ingredientpharm-700x240-1-300x103.pngBastian Arlt2022-07-05 14:43:022025-12-22 14:25:25Water-Insoluble Weakly Basic Actives on Tartaric Acid Beads – a DoE Case Study
APIs of BSC Class IV in oral formulations represent one of four…
https://tapellets.com/wp-content/uploads/2022/02/Cellets_BCS_class_IV.png6961459Bastian Arlthttps://tapellets.com/wp-content/uploads/2021/03/ingredientpharm-700x240-1-300x103.pngBastian Arlt2022-02-17 14:48:262025-12-22 14:26:22BSC Class IV APIs in oral formulations
Abstract
The objective of this study is to investigate the influence…
https://tapellets.com/wp-content/uploads/2021/03/API_TAP_formulation.png295462Bastian Arlthttps://tapellets.com/wp-content/uploads/2021/03/ingredientpharm-700x240-1-300x103.pngBastian Arlt2021-04-08 14:28:012022-04-12 13:49:44Influence of tartaric acid pellets on the release behavior of a basic drug
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