TAP are highly spherical starter pellets consisting of 100 % tartaric acid. They act as a pH modifier and as carrier systems in extended release formulations of weakly basic drugs. These drugs typically show bad solubility in higher pH environment such as in the lower intestinal tract which can be enhanced by the use of TAP as a starter core.

See pellet technologies for a detailed description.

TAPs allow high-level layering and coating. This induces a homogeneous distribution of APIs in multiparticular dosage forms. Advantages are:

+ narrow particle size distribution
+ even and dense surface
+ perfect sphericity
+ low friability
+ inertness

In conclusion, this means higher safety and better compliance for your patients, and added-value for your products.

Dissolution of Tartaric Acid Pelletsingredientpharm
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