Weakly basic drug show high dissolution behavior in lower pH regimes. pH-modifier serve a local environment in locations of higher pH. Tartaric acid pellets (TAP) is a powerful pH-modifier. TAPs are used in pellet technologies. Here, coating and layering of APIs and excipients can easily be formulated. In turn, the controlled release of weakly basic drug is enhanced.

Tag Archive for: ph-modifier


Influence of tartaric acid pellets on the release behavior of a basic drug

Abstract The objective of this study is to investigate the influence…

Tartaric acid starter pellets as pH-modifier for basic drugs

Introduction We will introduce tartaric acid starter pellets…