TAPs Introduction

TAPs means tartaric acid pellets. TAP provides an acidic localized environment upon dissolution in the GI tract. As weakly basic drug show high dissolution behavior in lower pH regimes, TAP acts as a pH-modifier for increased drug dissolution.

TAPs are used in pellet technologies. Here, coating and layering of APIs and excipients can easily be formulated. In turn, the controlled release of weakly basic drug is enhanced.

Several sizes of TAP starter cores are available ranging from 200 µm to 1000 µm.

TAPs offer safe and easy multi-particular soages forms. They can be employed in tablets, MUPS, sachets and mini-tablets. goto size information

Advantages

+ high control on time and place of drug delivery
+ low variability of gastric emptying
+ reduced risk of sudden dose dumping
+ low risk of localized high drug concentrations in the GI
+ lower intra- and inter-individual variability
+ low dependency on nutrition state

Case studies and application notes are available.

Manufacturers

Manufacturer of TAP is IPC Dresden/Germany. Please, forward your request for demand of standard or special sizes.

Tag Archive for: TAP

API_TAP_formulation

Influence of tartaric acid pellets on the release behavior of a basic drug

Abstract The objective of this study is to investigate the influence…
TAP_700_1ingredientpharm

Tartaric acid starter pellets as pH-modifier for basic drugs

Introduction We will introduce tartaric acid starter pellets…

Tag Archive for: TAP

TAP500-cross-light-400-320ingredientpharm

TAP 425-500

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TAP 400

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TAP 300-425

TAP500-cross-light-400-320ingredientpharm

TAP 300

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TAP 200